5. Therapeutic efficacy of Anti-malarial drugs in the treatment of uncomplicated malaria in Afghanistan, 2004-2007
Najibullah Safi, Awab Ghulam Rahim, Kamal Mustafa, Waqar Butt, Abdul Wasi Jawad, Tajwar Naseri, Rahmatullah
Routine anti-malarial drud resistant testing was conducted in three Malaria Reference Centers in Afghanistan using a standard WHO in vivo study design. Patients with confirmed uncomplicated P. falciparum were treated with sulfadoxin-pyrimethamin (SP) + Artesunate and followed for 28 day. Patients with P. vivax infection were treated with chloroquine (CQ) at standard dosage and followed for 28 days. All drugs tested showed greater than 95% efficacy, with SP+AS showing 100% acceptable clinical and parasitological response against P. falciparum and CQ showed 100% acceptable clinical and parasitological response against P. vivax.
Afghanistan Annual Malaria Journal (2009) P 50-53